X-ray generation by fs-laser processing of biological material

authored by
P. Mosel, J. Düsing, S. Johannesmeier, M. Patzlaff-Günther, S. Fröhlich, J. Mapa, S. Kalies, J. Bahlmann, T. Püster, J. Vahlbruch, G. Dittmar, H. Merdji, M. Fajardo, A. Trabattoni, A. Heisterkamp, U. Morgner, M. Kovacev
Abstract

The use of ultrashort pulse lasers in medical treatments is increasing and is already an essential tool, particularly in the treatment of eyes, bones and skin. One of the main advantages of laser treatment is that it is fast and minimally invasive. Due to the interaction of ultrashort laser pulses with matter, X-rays can be generated during the laser ablation process. This is important not only for the safety of the patient, but also for the practitioner to ensure that the legally permissible dose is not exceeded. Although our results do not raise safety concerns for existing clinical applications, they might impact future developments at higher peak powers. In order to provide guidance to laser users in the medical field, this paper examines the X-ray emission spectra and dose of several biological materials and describes their dependence on the laser pulse energy.

Organisation(s)
QuantumFrontiers
PhoenixD: Photonics, Optics, and Engineering - Innovation Across Disciplines
Ultrafast Laser Laboratory
Institute of Quantum Optics
Centre for Radiation Protection and Radioecology
External Organisation(s)
Laser Zentrum Hannover e.V. (LZH)
NIFE - Lower Saxony Centre for Biomedical Engineering, Implant Research and Development
Ingenieurbüro Prof. Dr.-Ing. G. Dittmar
Université Paris-Saclay
Universidade de Lisboa
Deutsches Elektronen-Synchrotron (DESY)
Type
Article
Journal
Biomedical optics express
Volume
14
Pages
5656-5669
No. of pages
14
ISSN
2156-7085
Publication date
09.10.2023
Publication status
E-pub ahead of print
Peer reviewed
Yes
ASJC Scopus subject areas
Biotechnology, Atomic and Molecular Physics, and Optics
Electronic version(s)
https://doi.org/10.1364/BOE.499170 (Access: Open)